Whoever wins the Head of the Charles this weekend, everyone in town’s a winner. Here’s why: 

LAUGH
Comedy for Life Benefit
What: Comics Carolyn Plummer, Ira Proctor, and Kelly MacFarland laugh it up to raise dough for the Deborah Winters Foundation, which helps Mass. residents living with breast cancer.
Why: When life hands you lemons, just laugh.
When: Sun., 6:45 p.m.
Where: The Comedy Connection, 1 Faneuil Hall Marketplace (617-248-9700).

BUY
Second Time Around’s Anniversary Sale
What: The designer clothing resale store turns 35 and passes the celebration on to you with 20 percent off new designer duds and an additional 20 off already reduced merchandise.
Why: It’s twice as good the second time.
When: Hours vary. Check website for store hours.
Where: All eight locations.

DO
Doggie Costume Party
What: Zen Dog Training awards prizes to pooches dressed in scary-cute costumes while their owners sample brews from Concord Brewery.
Why: Show off your mighty mutt with a superhero costume.
When: Sat., 3-6 p.m.
Where: Crate-Escape, 20 Flanders Rd., Belmont. R.S.V.P. at 617-233-5496.

EAT
Grafton Street Pub & Grill Turns 10
What: The beloved spot celebrates by serving up Irish specials like Dublin-style shepherd’s pie and hand-carved corned beef for $10.
Why: Get your ire up.
When: Thru Sun.
Where: 1230 Mass. Ave., Harvard Sq. (617-497-0400).

HEAR
Dragonfly
What: High-energy rock blended with Indian sitars from lead singer (and MIT grad) Miki Singh, plus other local rockers.
Why: Hear ye, hear ye.
When: Fri., 9 p.m.
Where: The Paradise Lounge, 969 Commonwealth Ave. Tickets at 800-594-8499.